Vuysiwa is a drama about Vuyiswa, a depressed and disgruntled transgender female who is adjusting to life as a female. Battling with loneliness and a pain staking bossy sister as a roommate, she struggles to find motivation in her life. This all changes when she meets David, a carefree sweet boy from her apartment who shares her love of books and the two spark a passionate relationship. Disturbed by the booming romance between Vuyiswa and an UN-informed David, Thando makes it her mission to expose Vuyiswa’s secret.