The Moneys have a quick turnaround when Eddie's agent calls about a big show in Reno. After struggling to get the family on the road and to the venue, Eddie and Laurie are faced with one more challenge when Jesse disappears moments before show time—forcing the band to go onstage without her.Meanwhile, Joe and Zach are left to hold down the homestead, wrangling the family's eight rowdy animals. Taking care of an abundance of pets proves to be more difficult than first imagined when Buddy, one of the family's many dogs, goes missing.