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The 49ers try to halt a four-game slide at Levi's Stadium as they welcome the Colts. San Francisco lost both its home games this season by a combined nine points. Indianapolis has won four straight meetings. The 49ers last defeated the Colts in 2001. |
Running
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| Title: | Indianapolis Colts at San Francisco 49ers | |
| Air Date: | October 24, 2021 | |
| Runtime: | 210 min | |
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