The Defenders is a drama about two colorful Las Vegas defense attorneys who go all-in when it comes to representing their clients. Nick and Pete are the local go-to guys with an eclectic client list who are still looking to hit their own jackpot. Leading the law firm of Morelli & Kaczmarek are Nick Morelli, an earnest, hard-charging attorney who represents his clients to the best of his ability, no matter how big or small the case; and his partner, Pete Kaczmarek, whose passion for the law is matched only by his love of fast cars, beautiful women and expensive clothes. Joining them in their growing law practice is new associate Lisa Tyler, an enthusiastic young attorney looking to put her exotic dancing days behind her; and their young assistant, Sophie, a spunky and sweet ingénue who is eager to please her bosses. While Lady Luck shines on their legal careers, the partners have their hands full when it comes to their personal lives. With Pete busy cruising the Vegas Strip for his latest romantic conquest, Nick is focused on repairing a fractured marriage to his estranged wife and remaining present in the life of their young son. No matter the offense, Nick and Pete aim to prove that when the stakes are high, they're willing to bet the house on the clients they defend in Sin City.