Celebrating Red Nose Day for the third year in a row, NBC has anchored a special night of programming on Thursday, May 25 with Chris Hardwick hosting the "The Red Nose Day Special" at 10:00 p.m. In addition, Academy Award winner Julia Roberts and other stars partake in Red Nose Day-themed programming throughout the night that both entertains viewers and gives them an opportunity to make a difference in the lives of kids in need."Celebrity Ninja Warrior for Red Nose Day" at 8:00 p.m. ET/PT is followed by a very special 9:00 p.m. episode of "Running Wild with Bear Grylls for Red Nose Day," with Roberts venturing to Kenya, leading up to NBC's third annual "The Red Nose Day Special," hosted by Hardwick at 10:00 p.m. The three shows are seamlessly tied together in celebration of Red Nose Day, with calls to action to donate throughout each of the three programs.Throughout the night, viewers will be entertained, learn about the programs supported by Red Nose Day that are helping to change the lives of children, and have the opportunity to support the charity through calls to donate, making a real difference for kids in need here in the U.S. and around the world. The one-hour "Red Nose Day Special," hosted by comedian Chris Hardwick, will be broadcast live from Rockefeller Plaza in New York City in support of the Red Nose Day charity campaign. Stars appearing include Ben Affleck, Jack Black, Orlando Bloom, Yvette Nicole Brown, Bryan Cranston, Patrick Dempsey, Akbar Gbajabiamila, Bear Grylls, Mindy Kaling, Mark Hamill, Matt Iseman, DJ Khaled, Matt Lauer, Rachel McAdams, Seth Meyers, Bobby Moynihan, Julia Roberts, Al Roker, Paul Rudd, Dax Shepard, Ben Stiller and Kenan Thompson, along with "This Is Us" cast members Milo Ventimiglia, Mandy Moore, Sterling K. Brown, Chrissy Metz, Justin Hartley, Chris Sullivan, Susan Kelechi Watson and Ron Cephas Jones.Shedding light on kids in need, Julia Roberts visits Africa and Paul Rudd visits rural Maine to show how children's lives can be changed and saved by Red Nose Day funds.The special will also feature "Red Nose Day Actually," the much-anticipated reunion sequel to "Love Actually," catching up with cast members from the beloved holiday film, including Colin Firth, Hugh Grant, Keira Knightley, Andrew Lincoln, Laura Linney, Liam Neeson and Bill Nighy.