The story of Sapho is laid in the Grecian era and Sapho is depicted as a wealthy woman of that period who has a host of admirers and a still greater host of maid servants who worship her. She is first seen playing the instrument which was most popular in her day the lyre, in her sumptuous apartments, surrounded by her maids. She receives a bunch of posies from an ardent admirer, but when he enters upon the scene she rejects him. She leaves her home and wanders through the beautiful country about the place, singing an extemporaneous song, as she plays upon her lyre. She finally wanders to the sea coast and watches a party of fishermen as they land in their small boat. She falls in love with one of their number, but finds, to her utter dismay, that he prefers a sweetheart among the common people of his country. She is disconsolate, and all that her doting maids can do to cheer her is of no avail. The film finally ends in her suicide upon the rocky coast.