After graduation, two young dentists can’t get a proper position with a dental partnership or a practice of their own. Dr. Moe Lars because of his low marks and Dr. Pierce Able because of his bad credit rating from his compulsive Internet gambling. Auntie Mae Lars has run out of money from sending her nephew Dr. Moe Lars to dental school and now setting him up in a rundown warehouse. Dr. Pierce Able funds his gambling with a new city incentive to give free dental care to welfare and low-income patients behind his partners back. After an ad for after-hours sharing of the dental location brings a few legitimate dentists who, once they see the type of street clients and working conditions, run away. After sunset, Dr. Drek Vam Dent, smooth and cold-handed, arrives and takes the dark hours dental shift. A gang of shadow-walker vampires harasses Dr. Vam Dent as his good service attracts both good and bad vampires with all types of ailments. Some vampires want to put the bite on Dr. Moe Lars when he comes to help the growing ‘night shift’. When Count Vam Dent brings an amulet for protection, Dr. Vam Dent decides to change some willing humans to the dark side.