Natasha, a journalist, gets a hunch and visits Dr. Kimura, the director of the institute, to find Rosa’s whereabouts. Natasha ventures to sneak into the institute at midnight, but Dr. Kimura is one step ahead and caught her. He puts her on his operation table and gives her a shot made from the cat DNA. Dr. Kimura raises her as savage Cat Girl. In the meantime, her best friend, Rosa, is raised as Cat Devil the Beast by Dr. Kimura. Now, Natasha and Rosa are subjects of the bidding on their fighting and meet face to face in the battle arena.