A wheelchair stands on the banks of the Rhine. Its owner has disappeared, leaving only a wallet behind. A suicide? A tragic accident? Or is it a crime? Lena Odenthal and Johanna Stern research the medical history of the disappeared and discover: everything points to suicide. But then the body of a doctor is found. She worked in brain research, where people with disabilities are supposed to regain mobility with the help of brain stimulation and where the missing wheelchair user also sought help. Lena and Johanna wonder if the self-confident, Nobel Prize-winning boss of the resident is involved in their case. He not only treats paralysis, but also has high-flying plans for the fusion of the human brain with artificial intelligence.
With Lena Odenthal, however, doubts about his credibility are growing. The possibilities of brain stimulation and the ambition of neuronal research are the subject of author and director Tom Bohn's "Tatort: Maleficius". In it, Sebastian Bezzel plays a researcher for whom everything seems possible in his impressive clinical world.