Seeing a dire need in the community for on-the spot medical assistance, LA County Firefighters Roy DeSoto and John Roderick "Johnny" Gage attempt to convince their staunchest opponent, Rampart General Hospital's Chief of Emergency Services, Dr. Kelly Brackett, to support paramedic legislation that means getting help to where it is needed most. Dr. Joe Early, an old friend of Dr. Brackett's, also lends his support to Johnny's & Roy's effort. Prior to running two separate calls with Johnny and Roy, their mentor, Rampart General Hospital's Chief Nurse of the Emergency Room, Dixie McCall, is injured and knocked unconscious.