Renowned anesthetist Raimund Weirath is found lifeless in the hospital's smoking area. The body shows signs of a fight, but there are no witnesses. The dead man's potential successor is Florian Groth. He is a former lover of Marie Brand. From him, the commissioners receive information that the murdered man was recently entrusted with a delicate task.Jessica, the daughter of former professional boxer Joe Kramer, is in a coma after an accident under general anesthesia and is declared brain dead. The task of the dead Weirath was to inform the parents about the hopeless condition of the child and to ask for approval for an organ donation. At the young girl's bedside, Marie and Simmel meet the mother Sybille Krämer and find out that she is not informed about her daughter's brain death. When asked about her ex-husband, she explains that Joe is in open custody and is on his way back to his cell. But he never arrives there and thus becomes the focus of the investigation. Then Marie finds out that there was also a dispute between Florian Groth and his superior about the Jessica case. When a witness reports

The decisive lead is then provided by the autopsy of the dead man. There are dried paint residues in his trachea. Was the man in the white coat perhaps not a doctor, but the master painter Stefan Fassbender, who was at the clinic with his daughter? Marie and Simmel learn that he too has lost a child. After talking to Weirath, they approved their daughter's body for organ donation. The loss of the child deeply traumatized the whole family. But is the master painter also the murderer?